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@whiteflame
Antibody titers are common practice. Beyond that, to say that the antibody production of another individual in no way informs your own doesn't make sense to me. If production is monitored across a broad set of people over a long period of time and found to be largely consistent, then yes, doctors can actually predict what will happen in you.
No, they cannot predict what will happen to me; they can guess what could happen to me.
I don't see how this is so, since a study like this necessarily must look at individuals. If I'm monitoring the production of antibodies after the administration of a vaccine and comparing it with an individual who receives a placebo, I'm looking at two individuals, not a population. If I continue to expand that outward and see this individual dynamic is true across a very large swath of patients, then saying that the vaccine induces an antibody response in the vast majority of patients receiving it is not an ecological inference fallacy. It's absolutely not an assumption.
I agree. But that is not what I'm referring to when I state that an ecological inference fallacy has been imputed. If across a very large swath of patients, it is observed that a vaccine has induced an antibody response in the vast majority of those who received said vaccine, and the argument is, "among those who've received the vaccine (thus far,) an antibody response has been induced in the vast majority of them," that's all well and good. However, if from that very same observation, it is argued, "person X should receive a vaccine, and since the vast majority of those who've received the vaccine have produced an antibody response, it is highly likely that person X will produce either the same antibody response or a sufficient antibody response to the virus, the chances of which are equal to the proportion which the vast majority represents," then that isn't all well and good. That is fallacious. It is an ecological intference fallacy--akin to the Division fallacy. The latter conclusion, no matter how extensive or meticulous the report/study is, will be based on an assumption which uses fallacious reasoning.
Antibody titers can be quantified. The rate of production of B cells with those antibodies when challenged with the virus can be quantified. The immune response to the virus following the initial and subsequently increased production of antibodies can be quantified. As for "How strong" it would have to be, that depends on a variety of factors, including the infectious dose received and how quickly the innate immune response is recruited. That certainly complicates things to a degree, but I don't think it invalidates the value of this specific immune response being effective against the virus.
My question on its being quantifiable was not based on the antibody count, but specifically your reference to the "strength" of an immune response, which you've relented relies on a variety of factors which presumably complicate its capacity to be quantified. So let me just ask this: is it possible that an unvaccinated person can produce a sufficient immune response to this COVID-19 virus?
A bit overdramatic.
Not at all, but I concede that this is not your burden.
Well, I appreciate that. I will say that I appreciate the thought you're putting into your responses, even when I personally disagree with what you're saying.
Same here.
I concede the possibility of it. It's also entirely possible that this is a natural strain. I have yet to see substantive evidence that leads me in either direction. The link you provided tells me that there are certainly human-modified pieces of coronaviruses that have been patented. That's true of basically any virus of note, as well as a great deal of bacteria, fungi and other organisms. I don't find that this tells much of a story, personally, especially since these weren't all functional viruses that could be released into the world and actively replicate in humans. I see amino acid sequences, various protein production methods and certain modified proteins, antivirals, protein complexes, antibodies, specific RNA interference methods, and some early vaccine stuff, much of which is likely directed at other coronaviruses that were coming up around that time. Several of those, including SARS-CoV-1 and MERS, are specifically mentioned. None of this looks particularly damning to me.
So this begs the question: what would you need to see in order for it to be damning? And what benchmarks would it need to satisfy?